Advances in Surgical Pathology: Endometrial Carcinoma - download pdf or read online

By Anna Sienko

ISBN-10: 1609131789

ISBN-13: 9781609131784

Part of the preferred Advances in Surgical Pathology sequence, this quantity is a concise, up to date assessment of the pathological features of endometrial melanoma. It emphasizes the histologic correlation, medical administration, and remedy of endometrial melanoma, and lines present and rising innovations within the box. The publication offers a source for the well timed updates in wisdom which are beneficial for day-by-day perform, for present credentialing, and for the self-assessment modules for recertification (MOC).

A unfastened significant other website positive aspects totally searchable textual content in addition to over a hundred thirty full-color images.

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Extra info for Advances in Surgical Pathology: Endometrial Carcinoma

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Overlapping glands or disruption of the stroma due to suboptimal histologic technique, such as improper fixation or processing and thick sectioning. 3. Poor orientation of the tissue can result in misinterpretation of irregularly shaped endometrial glands of the basalis or tangentially cut tortuous endometrial glands as endometrial hyperplasia (Fig. 3-14). 4. Telescoping is the intussusception of glands within glands due to mechanical disruption from curettage or biopsy. It can be seen in proliferative or secretory endometrium (Fig.

The glands are lined by proliferative epithelium, with some of the glands becoming enlarged or cystic. Some of the glands can have an irregular contour (Fig. 3 26 Section II • Histopathology FIGURE 3-10: Disordered proliferative endometrium. Note the glands of variable size and shape. There is no shift of the normal glandular-to-stroma ratio. 6 Secretory Endometrium Secretory endometrium can have an abnormal appearance due to artifactual crowding, fragmentation, or poor orientation of the tissue sample.

Note how the cells lining the neoplastic endometrial glands merge with the spindle cells (arrows). Chapter 4 • Endometrial Carcinoma 49 cells as a true sarcoma (Fig. 4-10A–B). The use of a keratin cocktail and epithelial membrane antigen (EMA) may assist in making the correct diagnosis; however, these immunostains can be only focally positive. CLEAR CELL CHANGES The cytoplasm of the neoplastic cells in endometrioid adenocarcinoma can be focally clear. 19 This type of neoplasm shows a proliferation of small glands lined by one or more layers of cuboidal, columnar, or flattened cells, with a variable amount of amphophilic or mucin-rich cytoplasm.

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Advances in Surgical Pathology: Endometrial Carcinoma by Anna Sienko

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