By Laura Mitchell
This booklet offers a concise, yet finished, advent to medical orthodontics. it's designed to entice either undergraduate dental scholars and the practicing dentist, and it really is either easy-to-read and entirely illustrated.
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Extra info for An Introduction to Orthodontics
The strength of fluorescent signal then reflects the level of gene expression. Proteomics There is not always a good correlation between the levels of mRNA and the amount of the corresponding protein. As proteins are the major effector molecules of the bacterial cell, measurement of proteins can provide a more accurate view of physiological and metabolic status. Early techniques separated proteins by electrophoresis (either 1D or 2D), and then proteins were identified by sequencing. However, these techniques lacked sensitivity.
Sucrose, glucose and fructose produce a more sustained and lower pH drop than some other sugars, such as lactose and starch. The bacterial metabolic pathways that lead to acid production from sugars are discussed in Chapter 18. Sucrose has the additional cariogenic property of providing a substrate for bacterial glucosyltransferases and fructosyltransferases. As discussed in Chapter 16, these enzymes produce polymers of glucan and fructan respectively from sucrose, both of which provide long-term energy storage.
Green boxes indicate no expression change. 22 Chapter 11 Systems approaches to oral microbiology As the complete genome sequences of oral bacteria are becoming available for an increasing number of organisms, it is now possible to explore bacterial processes such as pathogenicity on a global scale. Genomic sequence can be mined for genes or proteins that are differentially expressed under conditions relevant to disease, such as during infection in humans or in experimental animals, or in in vitro models.
An Introduction to Orthodontics by Laura Mitchell